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A study to establish whether a combination of surgery and radiation is effective in preventing recurrence of keloids

EFFICACY OF COMBINING SURGICAL EXCISION WITH ADJUVANT HIGH-DOSE-RATE (HDR) BRACHYTHERAPY IN PREVENTING RECURRENCE OF KELOIDS IN SOUTH INDIAN POPULATION

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020193
Enrollment
30
Registered
2019-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L989- Disorder of the skin and subcutaneous tissue, unspecified

Interventions

Intervention1: surgery followed by brachytherapy: surgical excision of the keloids will be done. Following surgery, brachytherapy will be instituted to the operated site within 48 hours following surg

Sponsors

MMC RGGGH Chennai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients presenting with keloid in any area of the body except joints. 2. Post surgical excision scar of keloid of more than or equal to 2cm in longest dimension. 3. Patients who are willing to be included in our study, who will accept the likely complications of irradiation after thorough counselling. The likely complications within the desired dosage of which are : I. Erythema, edema, desquamation, ulceration of skin. II. Pigmentary changes(hypo- or hyperpigmentation), atrophy,alopecia,telangiectasias and necrosis of skin.

Exclusion criteria

Exclusion criteria: 1. Unwilling patients. 2. Pregnant females and lactating mothers 3. Patients with medical conditions contraindicated to receive irradiation.

Design outcomes

Primary

MeasureTime frame
RECURRENCE RATETimepoint: june 2019

Secondary

MeasureTime frame
age skin typeTimepoint: 18 months

Countries

India

Contacts

Public ContactDr BADAMUTLANG DYMPEP

MADRAS MEDICAL COLLEGE

drssridevi@yahoo.com8575490028

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026