Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients with coronary artery disease undergoing elective coronary artery bypass grafting (CABG) without repair or replacement of other valves. 2. Patient operated for CABG first time.
Exclusion criteria
Exclusion criteria: 1. Patients below 18 years of age and > 70 years of age 2. Inadequate imaging of LV to interpret the results on CMR, intraoperative 2D TEE, or RT-3D TEE 3. Patients with dilated heart in whom we anticipate inadequate 3D TEE imaging 4. Patients with orthopnea 5. Patients not in sinus rhythm 6. More than mild mitral or aortic stenosis 7. More than mild pulmonary or tricuspid regurgitation 8. Concomitant repair or replacement of other valves 9. Patients having atrial septal defect, ventricular septal defect, patent ductus arteriosus or any significant pathology that will cause intra or extra cardiac shunting of blood 10. Re-do CABG 11. Incompatibility with cardiac MRI - patients having MRI incompatible implants or severe claustrophobia or patient unable to lie in the MRI gantry 12. Contraindication to TEE probe placement 13. Patient refusing to participate in the project
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To quantify and correlate the LV end-diastolic volume and LV end-systolic volume measured with intraoperative realtime three dimensional transesophageal echocardiography (RT-3D TEE) with those obtained from cardiac magnetic resonance (CMR) imaging 2. To compare and correlate the left ventricle ejection fraction (LVEF) obtained by intraoperative RT-3D TEE with those obtained from CMRTimepoint: Not applicable for this study as the outcome measures are evaluated during the pre-operative and intra-operative period and no further follow up is required | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To quantify and correlate the LV end-diastolic volume and LV end-systolic volume measured with intraoperative 2D TEE with those obtained from CMR imaging 2. To compare and correlate the LVEF obtained by intraoperative 2DE with CMRTimepoint: Not applicable for this study as the outcome measures are evaluated during the pre-operative and intra-operative period and no further follow up is required | — |
Countries
India
Contacts
Sree Chitra Tirunal Institute for Medical Sciences and Technology