ORAL MEDICATION IS AS EFFECTIVE AS INJECTABLE MEDICATION IN TREATMENT OF PNEUMONIA

COMPARISON OF EFFICACY OF ORAL AMOXICILLIN VERSUS PARENTERAL CEPHALOSPORIN IN TREATMENT OF UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA A PROSPECTIVE SINGLE BLINDED PARALLEL DESIGN,RANDOMIZED CONTROL TRIAL IN A TERTIARY CARE HOSPITAL OF METROPOLITAN CITY.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/07/020174

Enrollment

100

Registered

2019-07-15

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J189- Pneumonia, unspecified organism

Interventions

Intervention1: ORAL AMOXICILLIN : 100 MG/KG/DAY TDS 7 TO 10 DAYS Intervention2: INJECTABLE 3rd GENERATION CEPHALOSPORIN: 100 MG/KG/DAY BD FOR 7 TO 10 DAYS Control Intervention1: INJECTABLE 3rd GENERA

Eligibility

Inclusion criteria

Inclusion criteria: ALL CHILD IN THE AGE GROUP OF 6 MONTHS TO 12 YEARS ADMITTED IN PAEDIATRIC WARD AND CLINICALLY DIAGNOSED AS UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA IRRESPECTIVE OF ETIOLOGY.

Exclusion criteria

Exclusion criteria: 1. LESS THAN 6 MONTHS OF AGE. 2. CHILD ADMITTED IN PAEDIATRIC INTENSIVE CARE UNIT. 3. CHILD WITH UNDERLYING IMMUNODEFICIENCY INCLUDING ACQUIRED AND CONGENITAL CAUSES. 4. CHILD WITH CO-MORBID CONDITIONS LIKE DENGUE, MEASLES ETC. 5. CHILD WITH UNDERLYING HEREDITARY DISORDER LIKE CYSTIC FIBROSIS, SICKLE CELL DISEASE, DISORDERS OF CILIA ETC. 6. CHILD WITH UNDERLYING ANATOMICAL DISORDER LIKE PULMONARY SEQUESTRATION, LOBAR PNEUMONIA, GASTROESOPHAGEAL REFLUX DISORDER, TRACHEOESOPHAGEAL FISTULA AND BRONCHOPULMONARY DYSPLASIA.

Design outcomes

Primary

Measure	Time frame
COMPARISON OF EFFICACY OF ORAL AMOXICILIN VERSUS PARENTERAL CEPHALOSPORIN IN CASE OF UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA IN CHILDREN IN TERMS OF DAY OF DEFERVENSCENCE OF FEVER, DAY OF SETTLEMENT OF RESPIRATORY DISTRESS, DAY OF SUBSIDENCE OF COUGH, DURATION OF ANTIBIOTIC, DURATION OF HOSPITAL STAYTimepoint: 18 MONTHS	—

Secondary

Measure	Time frame
COMPARISON OF EFFICACY OF ORAL AMOXICILIN VERSUS PARENTERAL CEPHALOSPORIN IN CASE OF UNCOMPLICATED COMMUNITY ACQUIRED PNEUMONIA IN CHILDREN IN TERMS OF DAY OF DEFERVENSCENCE OF FEVER, DAY OF SETTLEMENT OF RESPIRATORY DISTRESS, DAY OF SUBSIDENCE OF COUGH, DURATION OF ANTIBIOTIC, DURATION OF HOSPITAL STAYTimepoint: 18 MONTHS	—

Countries

India

Contacts

Public ContactDR VAIJNATH T SATHE

GRANT GOVERNMENT MEDICAL COLLEGE AND SIR JJ GROUP OF HOSPITALS MUMBAI

vtsathe1@gmail.com7720905484

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026