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Sore throat reduction in the postoperative period by using drugs

A comparison of effect of nebulised ketamine and nebulised magnesium sulphate in reduction of incidence and severity of postoperative sore throat:a prospective randomised double blinded study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020158
Enrollment
70
Registered
2019-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: 8- Other Procedures

Interventions

Intervention1: Magnesium sulphate: 250mg of Magnesium sulphate mixed with 4ml of Normal saline given by nebulization for 15 minutes Control Intervention1: Ketamine: 50 mg of ketamine mixed with 4 ml N

Sponsors

Kanyakumari Government medical college hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA PS 1AND 2 BMI LESS THAN 30 WRITTEN INFORMED CONSENT

Exclusion criteria

Exclusion criteria: PATIENT REFUSAL ASA3 AND 4 ORAL CAVITY,NASOPHARYN,LARYNX AND NECK REGION SURGERIES SURGERIES REQUIRING PRONE POSITION ,SURGERIES LASTING FOR 3HRS H/O PREOP SORE THROAT COMMON COLD AND RECENT NSAID USE MMS MORE THAN 2 ASTHMA/ COPD MORE THAN ONE ATTEMPT AT INTUBATION AND TRAUMATIC INTUBATION

Design outcomes

Primary

MeasureTime frame
Incidence and severity of postoperative sore throatTimepoint: From time of extubation to till 24hrs after extubation—

Secondary

MeasureTime frame
EVALUATION OF SIDE EFFECTSTimepoint: FROM 0HRS TO 24HRS AFTER EXTUBATION—

Countries

India

Contacts

Public ContactRameshram

Kanyakumari Government medical college hospital asaripallam

edwardjohnson2310@gmail.com9443392974

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026