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To see if the enzymes released by leeches can dissolve thrombosis in portal vein.

Evaluation of Thrombolytic action of Jalaukavacharana in portal vein thrombosis secondary to Liver cirrhosis. A randomised single arm open labeled clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020156
Enrollment
10
Registered
2019-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K745- Biliary cirrhosis, unspecified Health Condition 2: D689- Coagulation defect, unspecified

Interventions

Intervention1: Jalaukavacharana: Application of 2 JalaukaS (leeches) at Right Upper quadrant of Abdomen every alternative days for a period 3 sitting i.e. total of 5 days. Control Intervention1: Nil:

Sponsors

RGUHS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects fulfilling the diagnostic criteria. 1) Subjects aged between 20-60 years irrespective of gender, religion will be selected. 2) Subjects Fit for Raktamokshana through Jaloukavacharana 3) Subjects having Normal INR values

Exclusion criteria

Exclusion criteria: 1)Subjects suffering from systemic disorders which would interfere with present study. 2)Subjects suffering from Portal Vein thrombosis arising due to malignant causes 3)Patient with Ascitis. 4)Surgical emergencies.

Design outcomes

Primary

MeasureTime frame
Resolution of thrombus.Timepoint: Resolution of thrombus at the end of 15 days—

Secondary

MeasureTime frame
Reduction in ascites Betterment of liver parametersTimepoint: 15 days—

Countries

India

Contacts

Public ContactDr Shashi Kiran

JSS Ayurvedic Medical College And Hospital

vaidya.shashikiran@gmail.com0821-254860

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026