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effect of injection teriparatide and tablet reunion in healing of jaw fracture.

Comparison of effect of subcutaneous injection of Teriparatide and combination of Cissus Quadrangularis and Dalbergia sissoo (Tablet Reunion ) on bone healing against control group in patients of maxillofacial fractures: A Randomized Open Label Control Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/07/020148
Enrollment
24
Registered
2019-07-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M279- Disease of jaws, unspecified

Interventions

Intervention1: subcutaneous injection of Teriparatide: Teriparatide is a recombinant parathyroid hormone 20 ug/day will be administered subcutaneously with modified insulin pen for 4 weeks after reduc

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients of either sex Age 18-60 years 2. ASA I or II 3. Patients of maxillofacial fracture including fracture mandible

Exclusion criteria

Exclusion criteria: 1. Age 60 years 2. Pregnant or lactating female 3. Hypercalcemia, pagetâ??s disease. 4. Malignant tumours 5. Patients earlier having radiation treatment. 6. Edentulous patients or patients with less than 50% of teeth.

Design outcomes

Primary

MeasureTime frame
1.pain-VAS score 2.mobility of fracture segments-0-mobility present,1-no mobility 3.bite force-flexi force sensorTimepoint: 1.pain-preoperatively,post operatively 1st,2nd,4th,6th week 2.mobility of fracture segment-preoperatively and postoperatively 1st,4th,8th week 3.bite force-preoperatively and postoperatively 1st,2nd,4th,6th,8th,12th week

Secondary

MeasureTime frame
1.blood investigations-serum calcium,PTH,ALP 2.Radiological assessment-ortho pantamogramTimepoint: 1.blood investigations-preoperatively and postoperative 4th week 2.radiological assessment-preoperatively and postoperatively on 1st day, 4th week, 8th week and 12th week

Countries

India

Contacts

Public ContactDR GIGI

AIIMS,jodhpur

ankitamody@gmail.com08003996891

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026