Health Condition 1: C00-D49- Neoplasms
Conditions
Interventions
None listed
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1) Head and Neck Cancer patients involving carcinoma of oral cavity, pharynx, larynx, para-nasal sinuses and salivary glands reporting in the Dental Department for Pre - NACT check up and providing consent. 2) Patients should be 18 or more than 18 years of age and diagnosed with malignancy in Head and Neck region. 3) Patients should be scheduled to undergo NACT by the Head and Neck DMG.
Exclusion criteria
Exclusion criteria: 1) Patients refusing to provide consent for the study. 2) Patients whose treatment is initiated prior to the observational study. 3) Patient unfit for providing consent and are in extreme discomfort or pain. 4) Patient has already undergone treatment for cancer previously and presently having recurrence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is to assess the oral and dental health status in head and neck cancer patients before, during and after NACT regimen.Timepoint: Time point for dental and oral status assessment with respect to NACT cycle: a) First assessment before treatment starts(baseline) b) Secondassessmenteight days after first cycle c) Third assessment after the last cycle is completed | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome is to compare the oral and dental health status in patients undergoing two different NACT regimens: Three drug combination (DCF) vs. two drug combination chemotherapy (DC) and to study the occurrence and intensity of pain of oral complications in the course of NACT regimen.Timepoint: Time point for dental and oral status assessment with respect to NACT cycle: a) First assessment before treatment starts(baseline) b) Second assessment eight days after first cycle c) Third assessment after the last cycle is completed | — |
Countries
India
Contacts
Public ContactDr Madhura Sharma
Tata Memorial Hospital
Outcome results
None listed