Health Condition 1: K00-K95- Diseases of the digestive system
Conditions
Interventions
Intervention1: Incremental Positive End Expiratory Pressure (PEEP ) titration: 10 minutes after laparotomy and abdominal retractor application, positive end expiratory pressure(PEEP)delivered by the v
Sponsors
All India Institute Of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: ASA physical status 1 and 2 Elective Major Abdominal Surgery( >2 hours) under General Anaesthesia
Exclusion criteria
Exclusion criteria: 1.Patients rfefusal to participate in the study. 2.Patients undergoing emergency laparotomy. 3.Known COPD or chronic lung diseases. 4.Known deformity of chest wall or thoracic spine. 5.Pre-existing significant cardiac,renal, and hepatic diseases 6.intraoperative massive blood loss( loss > 40 ml/kg) or massive transfusion ( > 8 PRBCs transfused ) 7.Patients on high dose ionotropes( Noradrenaline of 10 mcg/m or equivalent)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative atelectasis assessed by lung ultrasound in individualised PEEP titration group over fixed PEEP group.Timepoint: 10 minutes after extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Intraoperative and post operative oxygenation status(PaO2/FiO2) 2.Post operative atelectasis(10 minutes after extubation) 3.Incidence of intra operative bradycardia or hypotension 4.Incidence of Post operative pulmonary complication by Melbourne Group Scale( upto 3 days of surgery) 5.Number of patients needing supplemental oxygen to maintain SaO2 more than 95% 6.Length of postoperative hospital stay. Timepoint: Intraoperative time till discharge of patient. | — |
Countries
India
Contacts
Public ContactDr Souvik Maitra
All India Institute Of Medical Sciences
Outcome results
None listed