calculation of anaesthesia dose required required for making patient unconscious following adinistration of tablet melatonin ninety minutes before surgery

Effect of Melatonin On Dose Response of Propofol Used During Induction Of General Anaesthesia Using Bispectral Index

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/07/019998

Enrollment

Registered

2019-07-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Oral melatonin Tablet melatonin 6 mg: Tablet melatonin 6 mg 90 minutes before start of anesthesia Frequency only once Control Intervention1: Calcium with vitamin D: Elemental Calcium 25

Eligibility

Inclusion criteria

Inclusion criteria: American society of anaesthesiologist grade (ASA) 1&2 Patients posted for elective surgical anaesthesia

Exclusion criteria

Exclusion criteria: Patients refusal for procedure ASA grade III&IV Cardiac, renal, hepatic, neurological disorders Known hypersensitivity to propofol or melatonin Epileptic patients Pregnant patients

Design outcomes

Primary

Measure	Time frame
Calucate the induction dose of propofol requiredTimepoint: 2 years	—

Secondary

Measure	Time frame
Comparison of heamodynamic changes iTimepoint: 2 years	—

Countries

India

Contacts

Public ContactMahender P

Chettinad hospital and Research Institute

mprasad5987@gmail.com9840496490

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026