Health Condition 1: E669- Obesity, unspecified
Conditions
Interventions
Intervention1: Progressive resistance exercise: Progressive resistance exercise with nutritional intervention for a period of 6 months
Control Intervention1: Standard physical activity: Standard physi
Sponsors
Submitted to ICMR
Eligibility
Inclusion criteria
Inclusion criteria: Individuals between 30-60 years of age with BMI >=25 kg/m2, diagnosed to have sarcopenia based on the following definition of sarcopenia: 1 Appendicular skeletal muscle mass/height2: Men 2 Hand grip strength Men: 3 SPPB 4 4-minute gait speed
Exclusion criteria
Exclusion criteria: 1 Known or recently diagnosed diabetes mellitus or coronary heart disease 2 Contraindication to aerobic exercise or progressive resistance training 3 Any severe acute or chronic illness, severe end organ dysfunction, post organ transplant 4 Known malignancy, HIV/ HBsAg/Anti HCV positivity 5 Chronic alcohol use ( >30 g/day in men and >20 g/day in women) or any other drug abuse 6 Use of any medications that may affect the muscle function or mass such as corticosteroids, anabolic steroids, protein supplements, performance enhancing medications etc. 7 Pregnancy and lactation, any physical deformity or loss of extremity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in muscle mass and function in sarcopenic individualsTimepoint: At the end of 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in metabolic abnormalities such as insulin resistance, dyslipidemia and dysglycemiaTimepoint: At the end of 6 months | — |
Countries
India
Contacts
Public ContactDr Naval K Vikram
A.I.I.M.S., New Delhi
Outcome results
None listed