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Effect of single dose versus divided doses on the onset of action of a drug called Cisatracurium used for administration of general anaesthesia.

Effect of priming technique on onset of action and intubating conditions of cisatracuryum.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/06/019927
Enrollment
60
Registered
2019-06-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H662- Chronic atticoantral suppurative otitis media Health Condition 2: J440- Chronic obstructive pulmonary disease with acute lower respiratory infection Health Condition 3: null- Patients undergoing surgery under general anaesthesia

Interventions

Intervention1: Priming with cisatracurium: Patients primed with 0.01mg/kg of cisatracurium followed by 0.14mg/kg of cisatracurium after 3 minutes of priming interval Control Intervention1: Without pri

Sponsors

Nishma Monteiro
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 59 years. Males and females. American Society of Anesthesiologists(ASA)status 1 and 2. Undergoing surgery under general anaesthesia with endotracheal intubation.

Exclusion criteria

Exclusion criteria: Patient refusal. Pregnancy. Significant hepatic, renal and metabolic disorers and neuromuscular diseases. Known allergy to cisatracurium. Those with anticipated difficult intubation.

Design outcomes

Primary

MeasureTime frame
onset of action of cisatracurium in the 2 groupsTimepoint: at baseline, T1 is 15 seconds from baseline, T2 is 30 seconds from baseline, T3 is 45 seconds from baseline, T4 is 60 seconds from baseline.—

Secondary

MeasureTime frame
to study the intubating conditions in the different groupsTimepoint: Vitals will be monitored every 1 min from priming to intubation.—

Countries

India

Contacts

Public ContactNishma Monteiro

St. Johns medical college hospital

surbhi_pg@yahoo.com09880109361

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026