Ondansetron (Anti - emetic) vs Chewing gum for prevention of nausea and vomiting after Caesarean delivery

Ondansetron versus Chewing gum for prevention of post operative nausea and vomiting in patients undergoing Caesarean delivery : A randomized control trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/06/019923

Enrollment

100

Registered

2019-06-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: chewing gum: Per oral chewing gum for awake patients in the immediate post operative period Control Intervention1: Ondansetron: injection of Ondansetron 4mg intravenously immediately a

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient who gives written informed consent for study. 2. All patients ASA-I or ASA-II posted for elective cesarian delivey . 3 .Full term singleton pregnancy

Exclusion criteria

Exclusion criteria: 1. Patients refusing to participate in the study . 2. Essential hypertension/pre eclamsia. 3 . Diabetes. 4. Anemia 5. Heart disease 6, Multiple pregnancy. 7. Fetal distress 8. Abruption placenta/placenta pevia 9. contraindication to spinal anesthesia 10 Allergy to local anesthetics 11. Phenylketonuria (contraindication to the sweetener aspartame in chewing gum) . . 12.Women unable to chew gum either due to excessive sedation , or complaining of gum problems or tooth filling and women could be exposed to any intra-operative and post-operative complications.

Design outcomes

Primary

Measure	Time frame
Primary objective: To compare the efficacy of non medicated chewing gum with ondansetron in the management of PONV in patients under going cesarean delivery under spinal anesthesia Secondary objective: a) Time to first flatus, return of bowel motility and bowel sounds b) Length of hospital stay Timepoint: 6th, 12th and 24th hour post operatively	—

Secondary

Measure	Time frame
Secondary objective: a) Time to first flatus, return of bowel motility and bowel sounds b) Length of hospital stay Timepoint: postoperative period	—

Countries

India

Contacts

Public ContactDr Mohammed Sadiq

Bangalore Medical college and Research Institute

drmadhumala@gmail.com9886786768

Outcome results