A clinical study to see the effect of Ayurvedic drug in the management of Karnasrava w.s.r. to C.S.O.M.

A randomised clinical trial of Karnapichu with Gandhaka Taila, Karnadhupana and Rasnadi Guggulu in the managemaent of Karnasrava w.s.r. to chronic suppurative otitis media (C.S.O.M.)

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/06/019914

Enrollment

Registered

2019-06-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H661- Chronic tubotympanic suppurative otitis media

Interventions

Intervention1: Karnapichu with Gandhaka Taila along with Rasnadi Guggulu: Karnapichu (8 to 16 drops) twice a day for 30days and Rasnadi Guggulu (500 mg)twice daily for 30 days Control Intervention1: K

Eligibility

Inclusion criteria

Inclusion criteria: Patients presenting with signs and symptoms of karnasrava described as per Ayurvedic and modern parlance

Exclusion criteria

Exclusion criteria: 1. Age below 8 years and above 60 years. 2. Systemic diseases like uncontrolled DM, Meningitis,Tuberculosis,HTN etc 3. History of long term intake of ototoxic drugs 4. C.S.O.M. with complications like acute mastoiditis, petrositis, facial paralysis, adenoids, tonsilitis, labyrithitis etc. 5. Pregnant women.

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of Karnapichu with Gandhaka Taila,Karnadhupana and Rasnadi Guggulu in the management of Karnasrava(C.S.O.M.)Timepoint: 2 months	—

Secondary

Measure	Time frame
Any adverse event reported voluntarily, observed or enquired.Recurrence in sign and symptoms of Karnasrava(C.S.O.M.)Timepoint: 2 Months	—

Countries

India

Contacts

Public ContactDr Meena Nagar

National Institute Of Ayurveda

pamnani.gulab@gmail.com9461154942

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026