A study to compare the efficacy of jamun mouthwash on gum diseases and its comparison with chlorexidine mouthwash

Comparative evaluation of the efficacy of 5% Indian Jamun Extract and 0.2% Chlorhexidine Gluconate Mouthwash in Prevention of Plaque and Gingivitis among young adults: An In vivo In-vitro Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/06/019889

Enrollment

Registered

2019-06-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 5 % jamun mouthwash: to be used twice daily, 15ml each time, rinsing orally for 30 seconds for a period of 21 days Intervention2: 5 % Jamun mouthwash: to be used twice daily, 15 ml each

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects in age group of 18 to 30 years. 2. Subjects following routine oral hygiene procedures. 3. Subjects with mild to moderate gingivitis. 4.Subjects willing to participate in the present study.

Exclusion criteria

Exclusion criteria: 1.Subjects suffering from systemic diseases. 2.Subjects undergoing orthodontic treatments. 3.Subjects using other aids for oral hygiene apart from toothbrush. 4.Subjects having adverse habits like smoking, alcohol drinking. 5.Subjects not willing to participate in the present study.

Design outcomes

Primary

Measure	Time frame
To evaluate and compare in-vivo and in-vitro efficacy of 5% Indian Jamun extract..in vitro testing will be done on agar plates with 3 organisms (Streptococcus mitis porphyromonas gingivalis, tanerella forsythia) and in vivo testing will be done by taking plaque and gingival bleeding index at baseline, 7th day, 14th day and 21st day mouthwash with 0.2% Chlorhexidine gluconate mouthwash on plaque accumulation and gingivitis among young adults at baseline, 7th, 14th and 21st day. Timepoint: 7th, 14th and 21st day	—

Measure

Time frame

To evaluate and compare in-vivo and in-vitro efficacy of 5% Indian Jamun extract..in vitro testing will be done on agar plates with 3 organisms (Streptococcus mitis porphyromonas gingivalis, tanerella forsythia) and in vivo testing will be done by taking plaque and gingival bleeding index at baseline, 7th day, 14th day and 21st day mouthwash with 0.2% Chlorhexidine gluconate mouthwash on plaque accumulation and gingivitis among young adults at baseline, 7th, 14th and 21st day. Timepoint: 7th, 14th and 21st day

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Secondary

Measure	Time frame
1. To evaluate the efficacy of mouthwash containing 5% Indian Jamun extract on gingivitis and plaque accumulation and itâ??s comparison with 0.2% chlorhexidine gluconate mouthwash among young adults at baseline, 7th, 14th and 21st day (in vivo) using plaque index and gingival bleeding index 2.To evaluate the antimicrobial efficacy of mouthwash containing 5% Indian Jamun extract against Streptococcus mitis, Porphyromonas gingivalis and Tanerella Forsythia (in vitro) on agar platesTimepoint: 7th, 14th and 21st day	—

Measure

Time frame

1. To evaluate the efficacy of mouthwash containing 5% Indian Jamun extract on gingivitis and plaque accumulation and itâ??s comparison with 0.2% chlorhexidine gluconate mouthwash among young adults at baseline, 7th, 14th and 21st day (in vivo) using plaque index and gingival bleeding index 2.To evaluate the antimicrobial efficacy of mouthwash containing 5% Indian Jamun extract against Streptococcus mitis, Porphyromonas gingivalis and Tanerella Forsythia (in vitro) on agar platesTimepoint: 7th, 14th and 21st day

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Countries

India

Contacts

Public ContactDr Karina S Chachlani

A.C.P.M Dental College

drarundodamani@gmail.com7020669099

Outcome results