None listed
Conditions
Interventions
Intervention1: 1% chlorhexidine gluconate in aqueous form: Routine - Local application to skin
Dose- around 0.5 to 1 ml applied to skin and dried Frequency- once per enrollment
Duration- once
Baby
Sponsors
All India Instiute of Medical Sciences AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1) All inborn neonates from 26 0/7 - 42 6/7 weeks of gestation requiring NICU admission for at least 48 hrs 2) All extramural neonates from 26 0/7 - 42 6/7 weeks of gestation requiring admission in PICU/Pediatric surgery ICU/Pediatric HDU/Pediatric emergency irrespective of the duration of stay
Exclusion criteria
Exclusion criteria: 1) Hydrops 2) Generalised skin disorder 3) Skin infection 4) Severe persistent pulmonary hypertension 5) Sick baby requiring high ventilator support as adjudged by the clinical team
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the proportion of negative post cleansing skin swabs after the skin antisepsis performed by 1% aqueous chlorhexidine gluconate v/s 2 % aqueous chlorhexidine gluconate in neonates 26 0/7-42 6/7 weeks of gestation in first 28 days of lifeTimepoint: post antisepsis skin swab will be taken after 2 minutes of chlorhexidine application | — |
Secondary
| Measure | Time frame |
|---|---|
| Chlorhexidine level estimation in a subset of patientsTimepoint: at 6,12,24-48 hours after chlorhexidine application;To compare local skin reaction to chlorhexidine gluconate applicationTimepoint: At 0,6,12,24 hours after chlorhexidine application | — |
Countries
India
Contacts
Public ContactDr Anu Sachdeva
Division of Neonatology, Department of Pediatrics,AIIMS, New Delhi
Outcome results
None listed