Health Condition 1: K220- Achalasia of cardia
Conditions
Interventions
Intervention1: GERD-X group: Endoscopic full-thickness plication will be performed using the GERDX® system. All procedures will be performed under anesthesia. Guidewire will be placed into the stomac
Sponsors
Endoscopy Research Foundation
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of either sex aged 18-70 years and above 2. Aachalasia cardia patients minimum 3 months post POEM with abnormal 24hr pH metry, regardless of symptoms 3. Abnormal esophageal acid exposure defined as percentage time esophageal pH less than 4 of more than 4.2% on pH-metry during 24-h period while off PPI for atleast 1 week 4. Patients agreeing to informed consent
Exclusion criteria
Exclusion criteria: 1. Failed POEM â?? elevated integrated relaxation pressure and lower esophageal sphincter pressure 2. Hiatus hernia hills 3 or more 3. Patients with significant renal or liver disease 4. Grade D esophagitis 5. Barrettâ??s esophagus 6. ASA physical status >II 7. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of abnormal acid exposure by 24 hr ph studyTimepoint: 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in GERD-QTimepoint: 1 month and 3 months | — |
Countries
India
Contacts
Public ContactDr Gaurav Patil
Baldota Institute of Digestive Sciences
Outcome results
None listed