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to know the effectiveness of injectable therapy ( platelet rich plasma)in treatment of melasma

The comparative split face study of intradermal PRP injections v/s normal saline in the treatment of melasma - Melasma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/06/019813
Enrollment
74
Registered
2019-06-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L811- Chloasma

Interventions

Intervention1: Intradermal Platelet Rich Plasma: Platelet Rich Plasma is effective concentration of multiple fundamental growth factors (GFs) by virtue of platelets alone stored as alpha granules in p

Sponsors

Mahatma Gandhi Missions Medical College And Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with melasma 18 - 50 years and those who are willing for treatment

Exclusion criteria

Exclusion criteria: Pregnant females and females on OC pills. Patients with history of hypertrophic scars and keloids. Patients with recurrent Herpes simplex infection or with persistent cutaneous lesions. Patients with blood disorders Patients using systemic chemotherapy, anticoagulation therapy and antiplatelet agents. Patients with unrealistic expectations Patients on drugs causing melasma and who cant discontinue it. Patients with active acne Patients with localised active viral or bacterial infection

Design outcomes

Primary

MeasureTime frame
To study the comparative split face study of intradermal PRP V/S Normal saline in treatment of melasmaTimepoint: follow up every 3 weeks for 3 visits

Secondary

MeasureTime frame
Effect of Intradermal PRP in melasma patients is studied by comparing Modified MASI score before and after treatment. Also quality of life is assessed by MELASQOL scale before and after treattment.Timepoint: every 3 weeks for 9 weeks ( 2 months and one week )

Countries

India

Contacts

Public ContactADGulanikar

Mahatma Gandhi Missions Medical College And Hospital

agulanikar@hotmail.com9822377963

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026