Health Condition 1: G328- Other specified degenerative disorders of nervous system in diseases classified elsewhere
Conditions
Interventions
Intervention1: Brahmi Ghee: Classical formulation of Bramhi Ghrita as per Ayurvedic text (6gm,twice a day, for 3 months)
Control Intervention1: Ghee: Only Ghrita (6gm,twice a day, for 3 months)
Contro
Sponsors
Foundation for Revitalization of Local Health Traditions
Eligibility
Inclusion criteria
Inclusion criteria: i) MCI diagnostic criteria -- a) Change in cognition a concern for participant/informant b) Objective evidence of impairment c) Preservation of independence in functional abilities d) No evidence of dementia ii) Participants of both the genders above 55 years iii) Literate population (minimum 7th pass) iv) Participants on drugs (such as cholinesterase inhibitors) can be included only after a washout period for the drug. Decision to discontinue ongoing medication will be taken by clinicians upon the willingness of the participant. v) Participants undergoing Cognitive Training/Rehabilitation can be included if their ongoing training has not shown satisfactory improvements in symptoms, as assessed by the clinician,and upon willingness of the participant to discontinue the ongoing training to try an alternative treatment. vi) MRI (cortical thickness, temporal lobe atrophy, etc. â?? signs of degeneration)
Exclusion criteria
Exclusion criteria: i) Dementia ii) Depressive symptoms (Geriatric depression scale)/ psychiatric illness/ head injury iii) Alcohol/Drug Dependence iv) Hearing or visual impairment which can alter cognitive test outcome v) Uncontrolled diabetes ((HbA1C >7.0) vi) Hyper-lipidaemia (serum cholesterol >240mgs/dl, serum triglycerides >500, LDL >200) vii) Hypothyroidism viii) MRI (evidence of stroke, head injury, lesions) ix) Medications for MCI including Brahmi in any form x) Any other ongoing Ayurvedic treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in cognitive functions in Brahmi Ghee group compared to Plain Ghee and Placebo group.Timepoint: Baseline 1st follow up 2nd follow up post intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in cognitive functions in Brahmi Ghrita group compared to Comparative group (Brahmi extract).Timepoint: Baseline 1st follow up 2nd follow up post intervention | — |
Countries
India
Contacts
Public ContactBhaktee Dongaonkar
Institute of Ayurveda and Integrative Medicine
Outcome results
None listed