Health Condition 1: null- Compensated Cirrhosis
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Institute of liver and Biliary Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1)Age 18 to 75 years 2)Compensated cirrhosis 3)Biopsy proven cirrhosis or LSM > 12.5 Kpa.
Exclusion criteria
Exclusion criteria: 1) Any current or prior clinical decompesnation (ascites, jaundice, encephalopathy or gastrointestinal hemorrhage). 2) Pregnant Women 3) Hepatocellular Carcinoma 4) Known case of severe cardiopulmonary disease 5) Known case of severe Hepato Pulmonary Syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development of ascites, jaundice, encephalopathy or gastrointestinal hemorrhage) during the follow up period of 2 yeasTimepoint: 2 Years | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of patients develop Hepatic osteodystrophy during follow up period of 2 years. Timepoint: 2 Year;Number of patients develop hepatocellular carcinoma (HCC) during follow up period 2 years. Timepoint: 2 Year;Number of patients develop Hypersplenism during follow up period of 2 years. Timepoint: 2 Year;Number of patients develop Minimal Hepatic Encephalopathy (MHE) during follow up period of 2 years. Timepoint: 2 Year;Number of patients develop Pulmonary Syndrome (HPS) during follow up period of 2 years. Timepoint: 2 Year;Patients with new onset/progression of esophageal varices during the period of 2 yearsTimepoint: 2 Years;Reduction in portal pressure with more than 20% from baseline at 1 yearTimepoint: 1 Year;Reduction in portal pressure with more than 20% from baseline at 2 year.Timepoint: 2 Year;Reduction in portal pressure with more than 20% from baseline at 6 monthsTimepoint: 6 Months;Survival during the period of 2 years.Timepoint: 2 Year | — |
Countries
India
Contacts
Public ContactDr Ankit Bhardwaj
Institute of liver and Biliary Sciences
Outcome results
None listed