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to compare effect of streptokinase v/s saline wash in Lung Fluid

Non -Randomized parallel arm study to compare intrapleural instillation of streptokinase v/s placebo (Saline wash) in loculated empyema thoracis at a tertiary care centre

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/06/019720
Enrollment
56
Registered
2019-06-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J918- Pleural effusion in other conditions classified elsewhere

Interventions

Intervention1: DRUG (STREPTOKINASE),: STREPTOKINASE 15LAC/IU, IN FOUR DIVIDED (for Four Days Intrapleural) DOSAGES WITH DILUTED WITH 50ML OF NORMAL SALINE Control Intervention1: NORMAL SALINE 50 ML e

Sponsors

Department of Respiratory Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Consent • age > 12 years • 2)loculated empyema thoracis, patient attending in the department of respiratory medicine ,kgmu,up,lucknow

Exclusion criteria

Exclusion criteria: 1]Failure To Give Consent 2)Patient Below 12 Years Of Age 3)Simple And Single Loculated Empyema Thoracis 4)Patient With Icd In Situ Having Bronchopleural Fistula 5) Bleeding Disorders

Design outcomes

Primary

MeasureTime frame
Need for Surgery seen at the end of 14 days 1 month and 3 monthsTimepoint: Need for surgery—

Secondary

MeasureTime frame
Lung Expansion, total duration of hospital stayTimepoint: 3 MONTHS—

Countries

India

Contacts

Public ContactRajeev Garg

King George Medical University Lucknow

rajivkgmc@gmail.com9415002386

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026