Study of brain damage in newborns with increased sodium levels

A Study to evaluate MRI brain lesion in neonates with hypernatremia

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2019/06/019706

Enrollment

Registered

2019-06-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N19- Unspecified kidney failure

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Neonates (0 to 28 days) admitted with hypernatremia (serum sodium level >150mEq/l) will be included.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Neonate with: 1. Congenital malformations. 2. Suspected metabolic disease 3. known case of structural renal disease/previously diagnosed kidney disease 4. History of delayed cry/hypoxic ischemic encephalopathy 5. Sepsis screen or blood culture positive 6. Coagulopathy 7. Previous admission 8. History of abortion or unexplained sibling death in maternal history 9. History of stroke, DVT, early age MI or thromboembolic phenomena in family

Design outcomes

Primary

Measure	Time frame
To find out nature of intracranial pathology (brain lesion) in hypernatremic neonates and Correlation with clinical presentation and MRI brain Timepoint: Till 28 days of life	—

Secondary

Measure	Time frame
To find out correlation between location, number and types of lesion and degree of hypernatremia. To find out incidence mri brain changes of hypernatremia in sick neonates admitted in NICU of Umaid hospital.Timepoint: Till 28 days of life.	—

Countries

India

Contacts

Public ContactDr Anurag Singh

Dr. S.N Medical College, jodhpur

singhjodhpur@gmail.com9414133692

Outcome results