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Comparison Of Two Intravenous Sedative Drugs To Prolong Spinal Anaesthesia

The Effect Of Midazolam And Dexmedetomidine Sedation On Block Characteristics Following Spinal Bupivacaine : A Randomized Comparative Study

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/06/019605
Enrollment
100
Registered
2019-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration Health Condition 2: null- AMERICAN SOCIETY OF ANAESTHESIOLOGY GRADE 1 AND 2

Interventions

Intervention1: DEXMEDETOMIDINE: Dose 0.5 mcg per kg of body weight Route Intravenous Frequency once Control Intervention1: MIDAZOLAM: Dose 0.05 mg per kg body weight Route Intravenous Frequency once

Sponsors

Indira Gandhi institute Of Medical SciencesPatna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) Admitted cases at IGIMS, Patna b) ASA I and ASA 2 with no co morbidities c) Elective infraumblical surgery d) Aged between 20 and 60 years

Exclusion criteria

Exclusion criteria: a) Patient refusal b) Any opioids or sedative medication in the week prior to surgery . c) Coagulopathy or anticoagulant therapy d) Any cardiovascular disease and renal disease e) Increased intracranial tension. f) Pre-existing neurological disease & severe deformity of spine. g) Age 60yrs h) history of alcohol or drug abuse

Design outcomes

Primary

MeasureTime frame
intraoperative and post operative pain relief on intravenous dexmetomidine and intravenous midazolam.Timepoint: post operative-4hr, 8hr, 12hr, 24hr

Secondary

MeasureTime frame
any adverse effectTimepoint: 4hr,8hr,12hr,24hr

Countries

India

Contacts

Public ContactDr Mumtaz Hussain

Igims

drhussain72@yahoo.co.in9973152076

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026