Dexmedetomidine for sleeping ,Fentanyl and Nalbuphine for pain relief.A clinical trial comparing all three drugs in view of patient comfort during assessment of esophagus and stomach by using endoscopy.

Prospective Randomized double blinded study comparing Dexmedetomidine-Fentanyl with Dexmedetomidine-Nalbuphine for sedation and analgesia during upper gastrointestinal endoscopy procedure.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/06/019591

Enrollment

Registered

2019-06-10

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B- Imaging

Interventions

Intervention1: Dexmedetomidine and fentanyl: 1mcg per kg and 2mcg per kg only bolus dose intravenously 5 mins before procedure Control Intervention1: Dexmedetomidine and nalbuphine: 1mcg per kg and 0.

Eligibility

Inclusion criteria

Inclusion criteria: Patiens posted for upper gastrointestinal endoscopy Elective procedures ASA status one and two

Exclusion criteria

Exclusion criteria: Emergency procedure Patient not willing Allergic to drug Patient on chronic opioid ASA class three and four

Design outcomes

Primary

Measure	Time frame
Compare the sedation and analgesia effect in upper gastrointestinal endoscopyTimepoint: During procedure	—

Secondary

Measure	Time frame
Ease of procedure, discharge timeTimepoint: Before discharge	—

Countries

India

Contacts

Public ContactPrabu

SKS hospital and post graduate medical institute

gprabu_mmc@yahoo.co.in9884469456

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026