Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Ropivacaine 0.75%: 5 ml of Ropivacaine 0.75% for Nebulization
Control Intervention1: 0.9% Normal saline: 5 ml of 0.9% normal saline for nebulization
Sponsors
MIDNAPORE MEDICAL COLLEGE AND HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: Patients having ASA physical status I & II Patients of either sex Patients aged between 18 to 60 years Elective surgery less than or equal to 3 hours under general anaesthesia
Exclusion criteria
Exclusion criteria: Patientââ?¬•s refusal. Patients with difficult airway Patients who are allergic to any of the test drugs Patients with severe cardiovascular, respiratory, hepatic or renal dysfunction Recent history of respiratory tract infection History of chronic smoking Patients posted for emergency surgery. Patients with history of alcohol or drug abuse. Patients with more than one attempt of intubation. Duration of laryngoscopy and intubation >30 s Unexpected difficulty in ventilation or intubation Laryngospasm or bronchospasm occurrence Time span from completion of nebulization to intubation >20 mins
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Compare the hemodynamic responses during intubation 2. Compare the hemodynamic response during extubation and grade of post extubation cough. Timepoint: Hemodynamic response by measuring MAP, SBP, DBP, HR, SpO2 and EtCO2 Post extubation cough by a score of mild moderate and severe | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Time to extubation (Time from anaesthetic withdrawal to the removal of endotracheal tube) 2.Post-operative sore throat (POST) 3.Agitation during recovery (Ramsey Sedation Score) 4.Nausea and vomiting, 5.Other complications Timepoint: POST by Grade 0,1,2,3 Pain by VAS | — |
Countries
India
Contacts
Public ContactDr Sandip Roy Basunia
MIDNAPORE MEDICAL COLLEGE AND HOSPITAL
Outcome results
None listed