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MRI findings in diabetic peripheral neuropathy before and after nerve mobilization

Diffusion Tensor Imaging values in posterior tibial nerve in healthy controls and patients with Diabetic Peripheral Neuropathy: Pre and Post Nerve Mobilization

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/06/019552
Enrollment
90
Registered
2019-06-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E114- Type 2 diabetes mellitus with neurological complications

Interventions

Intervention1: Nerve massage, Neural Mobilization (slider and tensioner technique of tibial nerve),TENS: Patient position-supine lying Procedure- The therapist will hold patient lower extremity in the
knee extension and proper stabilization will be provided to the remaining lower extremity joints.At the end of nerve bias, DF of the foot and toes will be released in the plantar flexion movement to a

Sponsors

Maharishi Markandeshwar Deemed to be University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Individuals with confirmed chronic sensory motor diabetic peripheral neuropathy (CSMDPN) diagnosed by physician as per diagnostic criteria. 2.Individuals with unilateral or bilateral CSMDPN. 3.Individuals who will give the informed consent. 4.Individuals with Type 2 diabetes,with HbA1C <10%.

Exclusion criteria

Exclusion criteria: 1.History of cardiac pacemakers and MRI contraindications. 2.Diabetic foot ulcer. 3.Any deformity induced due to musculokeletal or neurological involvement. 4.Central nervous system and autonomic nervous system pathology. 5.Any other co morbidities

Design outcomes

Primary

MeasureTime frame
Fraction Anisotropy, Apparent Diffusion CoefficientTimepoint: 2 time points- baseline and after 3 weeks

Secondary

MeasureTime frame
VAS, Neuro-QoLTimepoint: 2 time points - baseline and 3 weeks

Countries

India

Contacts

Public ContactDr Amit Mittal

MMIMS&R, MM(DU)

amitmittalrad@yahoo.co.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 20, 2026