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To compare the effect of Dexmedetomidine and Labetalol on hemodynamic changes during laryngoscopy and intubation

A Comparative study for attenuation of hemodynamic responses to laryngoscopy and intubation with Dexmedetomidine and Labetalol in Laparoscopic Cholecystectomy surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/06/019544
Enrollment
90
Registered
2019-06-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: All the cases will be divided into 3 groups of 30 each(Computer generated randomised number): Group A will receive 0.5mcg/kg intravenously Dexmedetomidine diluted with Normal saline. Th

Sponsors

Mousumi Das
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA-I AND ASA-II

Exclusion criteria

Exclusion criteria: Hypertension, Diabetes, COPD, Ischemic heart disease ,Patients on Beta blocker,Heart block ,Cases of baseline sinus bradycardia, Allergic to study drug, BMI >30, Pregnancy,Difficult airways, Emergency surgeries

Design outcomes

Primary

MeasureTime frame
To find a simple and safe method for diminishing the incidence and severity of cardiovascular reaction to larngoscopy and tracheal intubation which would be of clinical importance in anesthetic practiceTimepoint: 6 months—

Secondary

MeasureTime frame
NATimepoint: 6 months—

Countries

India

Contacts

Public ContactDr Mousumi Das

Kalinga Institute Of Medical Sciences, Bhubaneswar, Orissa

mousumi.das1503@gmail.com7750847478

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026