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A study to compare the efficacy of radiofrequency ablation and platelet rich plasma injection for the treatment of low back pain

Comparative evaluation of efficacy of intervertebral disc radiofrequency ablation (RFA) and platelet rich plasma (PRP) injection for discogenic low back pain: a prospective randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/06/019531
Enrollment
52
Registered
2019-06-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M513- Other thoracic, thoracolumbar andlumbosacral intervertebral disc degeneration

Interventions

Intervention1: Intradiscal Platelet Rich Plasma (PRP) injection: 2ml PRP in involved disc for treatment of discogenic pain Control Intervention1: Radiofrequency ablation of intervertebral disc: Radiof

Sponsors

Institute of Medical Sciences BHU Varanasi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA 1 and 2 patients with > 6 months low back ache 2. Not responding to conservative management (medications, physical therapy, steroid injections) 3. Discogenic pain suggested by clinical and radiological (MRI) diagnosis 4. Concordant pain on discography

Exclusion criteria

Exclusion criteria: 1. Radicular pain more than back pain 2. Spinal canal stenosis 3. Spondylosis and Spondylolisthesis 4. Other causes of low back pain (facet osteoarthritis, sacroiliac joint arthrpathy) 5. Coagulation disorders or patient on anticoagulants 6. Pregnancy 7. Extruded or sequestered disc 8. Previous spinal surgery 9. Skin infection 10. Psychiatric illness 11. Patients having an annular tear with contrast spreading into epidural space

Design outcomes

Primary

MeasureTime frame
Numeric Rating Scale (NRS) for pain and Oswestry Disability Index (ODI) scoreTimepoint: Baseline, at 3 and 6 months post procedure—

Secondary

MeasureTime frame
1. Variation in analgesic requirement over time 2. Complications and adverse effects will be notedTimepoint: baseline and up to 6 months post procedure—

Countries

India

Contacts

Public ContactDr Anil Kumar Paswan

Sir sunderlal hospital, BHU

dranil1973@gmail.com9794855871

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026