Effect of dexmedetomidine in agitation after nasal operation

Role of dexmedetomidine infusion on post operative emergence agitation and quality of recovery after nasal surgery :a prospective randomized double blind controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/06/019502

Enrollment

Registered

2019-06-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J399- Disease of upper respiratory tract, unspecified

Interventions

Intervention1: Dexmedetomidine: alpha-2 adrenergic agonist infusion given @ 0.4 microgm/kg/hour Control Intervention1: Normal saline: volume matched as placebo

Eligibility

Inclusion criteria

Inclusion criteria: Adult male or female age between 18 to 60 years ASA grade IorII Patients undergoing nasal surgery in which nasal packing until 24 hour after surgery

Exclusion criteria

Exclusion criteria: patient refusal Allergy to alpha-2 adrenergic agonist or NSAIDS BMI >30 kg/m2 chronic kidney or liver disease cognitive impairment chronic use of antipsychotic medication

Design outcomes

Primary

Measure	Time frame
Evaluation of post operative agitation level using ricker sedation agitation scale Grade of cough at the time of extubation Quality of recovery using 15 item quality of questonnarieTimepoint: at 5, 10, 15, 30, 60, 90, 120 minutes after extubation	—

Secondary

Measure	Time frame
Extubation time Pain evaluation using 11 point numerical rating pain scale Nausea and vomiting using 4 point nausea vomiting scaleTimepoint: at 5, 10, 15, 30, 60, 90, 120 minutes after extubation	—

Countries

India

Contacts

Public ContactDr Lopa Trivedi

Government medical college bhavnagar

trivedi_lopa@yahoo.in9428009958

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026