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Effects of cleaning of teeth on beta cell activation factor levels among ex-smokers ,smokers and nonsmokers with gum disease

EFFECT OF NON-SURGICAL PERIODONTAL THERAPY ON BETA- CELL ACTIVATION FACTOR LEVELS AMONG FORMER SMOKERS,SMOKERS AND NONSMOKERS WITH CHRONIC PERIODONTITIS - ENSPTBAFF

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019459
Enrollment
30
Registered
2019-05-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: serum BAFF among smoker,nonsmokers and former smoker: Periodontal disease is one of the most common chronic disease in adults. Tobacco smoking mostly in the form of cigarette smoking is
cluster of differentiation 257).As an immunostimulant, BAFF (BLyS, TALL-1) is necessary for maintaining normal immunity. Inadequate level of BAFF will fail to activate B cells to produce enough immuno

Sponsors

panineeya institute of dental science
Lead Sponsor
P VEERENDRANATH REDDY
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged between 25-50 years of age. 2. Patients with at least 15 natural teeth remaining. 3. Patients suffering from chronic periodontitis (>= 5mm pocket Depth or >= 3mm loss of attachment) were selected. 4 .History of smoking. Former smoker-An adult who has smoked at least 100 cigarettes in his life time but since one year has not smoked . Smoker-An adult who has smoked 100 cigarettes in his lifetime but who currently smokes cigarettes every day or on some days. Nonsmoker- No habit of smoking.

Exclusion criteria

Exclusion criteria: 1.Chronic systemic pathology, such as diabetes, other endocrine Pathologies, hematological pathologies. 2.Subjects on antibiotics or anti-inflammatory drugs within the last 6 Months. 3.Subjects who underwent professional cleaning/ periodontal Treatment within the last 6 months or diagnosed with aggressive Periodontitis.

Design outcomes

Primary

MeasureTime frame
effect of serum BAFF level among former smoker,smoker,and nonsmokerTimepoint: at baseline

Secondary

MeasureTime frame
effect of serum BAFF level among former smoker,smoker,and nonsmokerTimepoint: at 3 months

Countries

India

Contacts

Public Contactricha shalya

PANINEEYA INSTITUTE OF DENTAL SCIENCES AND RESEARCH CENTRE

richa.cods@gmail.com7675962882

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026