Health Condition 1: C672- Malignant neoplasm of lateral wallof bladder
Conditions
Interventions
Intervention1: Dexmedetomidine infusion 1: Dexmedetominidne 1.0ug/kg iv followed by 0.8ug/kg/min.
Intervention2: Dexmedetomidine 2: Dexmedetomidine 0.7ug/kg iv followed by 0.5ug/kg/min.
Control Interv
Sponsors
none
Eligibility
Inclusion criteria
Inclusion criteria: 1 ASA-1&2 2 Patients undergoing elective TURBT under general anaesthesia
Exclusion criteria
Exclusion criteria: 1 Female patients 2 Patients undergoing emergency surgery 3 Refusal by the patients 4 Patients with bladder outflow obstruction or overactive bladder (frequency greater than three times per night or more than eight times per 24 h) 5 Patients having autonomic neuropathy 6 Patients with renal dysfunction (serum creatinine >1.6mg/dl) 7 Patients with neurogenic bladder 8 Heart failure and arrhythmia 9 Morbid obesity 10 Patient with hepatic dysfunction 11 Known allergy to the study drug 12 Patient affected with any psychiatric illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Presence or absence of CRBD 2. Severity of CRBDTimepoint: 0,2,6,12,24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Level of sedation by The Ramsay Sedation Scale 2. Post operative Pain Recorded using a numerical rating scale (NRS) 3. Postoperative nausea and vomiting 4. Dry mouth 5. Haemodynamic parameters Timepoint: 0 ,2, 6, 12 & 24 hr | — |
Countries
India
Contacts
Public ContactDr SPAmbesh
SGPGIMs, Lucknow
Outcome results
None listed