Health Condition 1: K353- Acute appendicitis with localizedperitonitis
Conditions
Interventions
Intervention1: Injection Cisatrcurium: Cisatracurium is also non depolarizing muscle relexant with more potency and slower onset of action with 30 to 60 minute of duration of action.
it releases very
Sponsors
Government medical college Bhavnagar
Eligibility
Inclusion criteria
Inclusion criteria: 1)Informed written consent 2)18 to 50 years of age 3)Patient is of either gender 4)ASA physical status I and II 5)Undergoing elective laproscopic appendicectomy 6)Requiring endotracheal intubation
Exclusion criteria
Exclusion criteria: 1)Refusing to give consent 2)Anticipated difficult airway 3)Pre existing liver or renal failure 4)Therapy with drug known to interfere with neuromuscular transmission 5)Antenatal and lactating females 6)Prolonged preoperative bed rest 7)Patient having neuromuscular disorders 8)ASA physical status III and IV
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Time of onset of action 2)Intubation time 3)Time interval between loading and first maintenance dose 4)Time interval between maintenance doses 5)Extubation time 6)Total number of doses required Timepoint: 1)Noted when TOF count is reduced to 3 on PNS afer giving loading dose 2)Noted when no response to TOF on PNS after giving loading dose 3)Noted when TOF count is more than 2 on PNS after giving loading dose 4)Noted when TOF count is more than 2 on PNS after giving top up dose of drug 5)Noted from end of the operation to extubation and TOF count is 4 on PNS | — |
Secondary
| Measure | Time frame |
|---|---|
| Haemodynamic effects( pulse, non invasive blood pressure monitoring)Timepoint: Baseline 5 min. after inj. fentanyl After intubation At 10 min. ,20 min.,30 min.,60 min.,90 min. ,120 min., At the end of operation At extubation 2 min. after extubation | — |
Countries
India
Contacts
Public ContactDr Nimisha Tank
Government medical college Bhavnagar
Outcome results
None listed