Corelation of platelet count of platelet rich plasma in improvement of low back pain caused by spinal disc

Intradiscal platelet rich plasma (PRP) injection for discogenic low back pain and correlation with platelet concentration: a prospective clinical trialâ??

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/05/019434

Enrollment

Registered

2019-05-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M513- Other thoracic, thoracolumbar andlumbosacral intervertebral disc degeneration

Interventions

Intervention1: Intradiscal platelet rich plasma (PRP) injection: Five to Six ml of PRP will be prepared in a sterile manner by aspirating 20 ml of blood from the patient. The PRP prepared will then be

Eligibility

Inclusion criteria

Inclusion criteria: 1. >6 months of low back ache 2. not responding to conservative management (medications, physical therapy, steroid injections) 3. Concordant pain on discography

Exclusion criteria

Exclusion criteria: 1. Radicular pain more than back pain 2. Spinal canal stenosis 3. Spondylosis and Spondylolisthesis 4. Other causes of low back pain 5. Coagulation disorders or patient on anticoagulants 6. Pregnancy 7. Extruded or sequestered disc 8. Previous spinal surgery 9. Skin infection 10. Psychiatric illness

Design outcomes

Primary

Measure	Time frame
1. Numerical rating scale (NRS) for pain and Oswestry disability index (ODI) score before the procedure and at 3 and 6 months post procedure. 2. Platelet count of the patient and PRP sample will be noted and correlated with the improvement in back pain Timepoint: 1. NRS and ODI score before the procedure and at 3 and 6 months post procedure. 2. Platelet count of the patient and PRP sample will be noted and correlated with the improvement in back pain	—

Measure

Time frame

1. Numerical rating scale (NRS) for pain and Oswestry disability index (ODI) score before the procedure and at 3 and 6 months post procedure. 2. Platelet count of the patient and PRP sample will be noted and correlated with the improvement in back pain Timepoint: 1. NRS and ODI score before the procedure and at 3 and 6 months post procedure. 2. Platelet count of the patient and PRP sample will be noted and correlated with the improvement in back pain

—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr Nimisha Verma

Institute of Medical Sciences, BHU, Varanasi

verma.nimisha5@gmail.com9559955988

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026