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Comparison of nitroglycerin spray and lignocaine spray for attenuating the pressor response during laryngoscopes and endotracheal intubation in patients undergoing elective surgery under general anaesthesia

Comparison of nitroglycerin spray and lignocaine spray for attenuating the pressor response during laryngoscopes and endotracheal intubation in patients undergoing elective surgery under general anaesthesia

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019430
Enrollment
70
Registered
2019-05-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: not applicable: not applicable Control Intervention1: NITROGLYCERINE SPRAY vs LIGNOCAINE SPRAY : NITROGLYCERINE SPRAY 0.4mg- 1 puff , LIGNOCAINE SPRAY 10mg- 2 puffs duration of action

Sponsors

Dr Balasandhiya p
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: AMERICAN SOCIETY OF ANAESTHESIOLOGY (ASA) I & II

Exclusion criteria

Exclusion criteria: PREGNANT PATIENT HISTORY OF CARDIOVASCULAR DISEASE HISTORY OF HEPATIC AND RENAL DISORDER PATIENTS WHO ARE ALLERGIC TO TEST DRUG BMI MORE THAN 30 ANTICIPATED DIFFICULT AIRWAY HYPERTENSIVE PATIENTS ON ANTIHYPERTENSIVE MEDICATIONS

Design outcomes

Primary

MeasureTime frame
50Timepoint: 4 weeks—

Secondary

MeasureTime frame
70Timepoint: 1 YEAR—

Countries

India

Contacts

Public ContactDr Balasandhiya P

Chettinad hospital and research institute

sandhiya.prabakar@gmail.com9444125703

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026