Health Condition 1: J470- Bronchiectasis with acute lower respiratory infection
Conditions
Interventions
Intervention1: Nebulised tranexamic acid arm: Nebulised arm would receive
500mg(5ml) of nebulized TA mixed with 5 ml of distilled water stat
followed by 500mg TA nebulised TDS . The osmolarity of TA i
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Adult( >18years) patients presenting to the Emergency Department with active hemoptysis.
Exclusion criteria
Exclusion criteria: 1) Patients already received tranexamic acid before presenting to the hospital. 2) Intubated patients on mechanical ventilation. 3) Patients with massive life-threatening hemoptysis who need to be immediately shifted for interventional procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cessation of bleeding in patients presenting to ED with active hemoptysis at 30 minutes after initiation of treatment.Timepoint: 30 minutes after initiation of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Need for urgent interventional procedures â?? Bronchoscopy and bronchial artery embolization(BAE).Timepoint: Time of interventional procedure;2. Reduction in volume of hemoptysis at 6, 12 and 24 hours after presenting to Emergency department(ED).Timepoint: 6,12 and 24 hours | — |
Countries
India
Contacts
Public ContactPraveen Aggarwal
AIIMS, New Delhi
Outcome results
None listed