Clinical Trial Assessing Efficacy of Virgin Coconut Oil in Preventing Radiation Mucositis in Patients with Head and Neck Cancer

Double Blind Randomized Controlled Trial Comparing the Efficacy of Virgin Coconut Oil with Artificial Saliva in Preventing Radiation Mucositis and Improving Quality of Life in Patients with Head and Neck Cancers

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/05/019319

Enrollment

200

Registered

2019-05-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: Virgin Coconut Oil: The participants will be instructed to rinse their mouth with 5ml of the medication for 2 minutes, 5 times in a day starting from the first day of radiotherapy till

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Head and Neck Cancers Scheduled to Undergo Radiotherapy, Willing to Participate in the study, Informed Consent

Exclusion criteria

Exclusion criteria: Patients with Cancers involving sites other than Head and Neck, Patients Not willing to Participate in the study

Design outcomes

Primary

Measure	Time frame
1 Statistically Significant Effectiveness of Virgin Coconut Oil in Prevention of Radiation Mucositis as Compared to Artificial Saliva in Head and Neck Cancer Patients scheduled to undergo Radiotherapy 2 Statistically Significant Effectiveness of Virgin Coconut Oil in Improving Quality of Life Scores as compared to Artificial Saliva in Head and Neck Cancer Patients scheduled to undergo RadiotherapyTimepoint: END OF EVERY WEEK OF RADIOTHERAPY TILL COMPLETION OF RADIOTHERAPY	—

Measure

Time frame

1 Statistically Significant Effectiveness of Virgin Coconut Oil in Prevention of Radiation Mucositis as Compared to Artificial Saliva in Head and Neck Cancer Patients scheduled to undergo Radiotherapy 2 Statistically Significant Effectiveness of Virgin Coconut Oil in Improving Quality of Life Scores as compared to Artificial Saliva in Head and Neck Cancer Patients scheduled to undergo RadiotherapyTimepoint: END OF EVERY WEEK OF RADIOTHERAPY TILL COMPLETION OF RADIOTHERAPY

—

Secondary

Measure	Time frame
Statistically Significant Effectiveness of Virgin Coconut Oil in Prevention of Radiation Mucositis as Compared to Artificial Saliva in Head and Neck Cancer Patients scheduled to undergo Radiotherapy 2 Statistically Significant Effectiveness of Virgin Coconut Oil in Reducing Salivary Candidal carriage as compared to Artificial Saliva in Head and Neck Cancer Patients scheduled to undergo Radiotherapy Timepoint: ASSESSMENT AT END OF EVERY WEEK OF RADIOTHERAPY TILL COMPLETION OF RADIOTHERAPY	—

Measure

Time frame

Statistically Significant Effectiveness of Virgin Coconut Oil in Prevention of Radiation Mucositis as Compared to Artificial Saliva in Head and Neck Cancer Patients scheduled to undergo Radiotherapy 2 Statistically Significant Effectiveness of Virgin Coconut Oil in Reducing Salivary Candidal carriage as compared to Artificial Saliva in Head and Neck Cancer Patients scheduled to undergo Radiotherapy Timepoint: ASSESSMENT AT END OF EVERY WEEK OF RADIOTHERAPY TILL COMPLETION OF RADIOTHERAPY

—

Countries

India

Contacts

Public ContactNatarajan Kannan

Narayana Dental College and Hospital

asokansharath@gmail.com9840168772

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026