Health Condition 1: F330- Major depressive disorder, recurrent, mild Health Condition 2: F331- Major depressive disorder, recurrent, moderate Health Condition 3: F320- Major depressive disorder, singleepisode, mild Health Condition 4: F321- Major depressive disorder, singleepisode, moderate
Conditions
Interventions
Intervention1: Active Prefronto-cerebellar transcranial direct current stimulation: Ten sessions of active Prefronto-cerebellar tDCS, twice a day, 2 hours apart, 20 mins each, giving 2 mA of current p
Sponsors
Manipal University
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with mild and moderate depression according to ICD 10 criteria 2. Patients who are able to give written informed consent to undergo tDCS 3. Patients of either gender 4. Patients who have been administered a stable dose of antidepressants and/or antipsychotic/mood stabilizers for at least 2 weeks 5. At least five years of formal education (primary level)
Exclusion criteria
Exclusion criteria: 1. Psychiatric co-morbidities, which will be ruled out using the MINI PLUS scale (Excluding Tobacco Dependence Syndrome) 2. Patients not willing to give consent 3. Advanced liver, kidney, cardiac or pulmonary diseases 4. Contraindications to tDCS e.g. metal or medical devices implanted in the body 5. Patients with a history of seizures 6. Patients in remission i.e. patients with a baseline HAM-D score of 7. Patients with Severe Depression 8. Patients with a history Bipolar disorder 9. Patients on Benzodiazepines at the time of tDCS procedure
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Reduction in depressive score â?¥50% HAM-D and IDS scores in patients receiving tDCS. Timepoint: 4 weeks | — |
Primary
| Measure | Time frame |
|---|---|
| Change in neurocognitive functions in patients receiving tDCSTimepoint: 4 weeks | — |
Countries
India
Contacts
Public ContactRuthshee Suresh
Kasturba Medical College, Manipal
Outcome results
None listed