Health Condition 1: O368- Maternal care for other specifiedfetal problems
Conditions
Interventions
Intervention1: Magnesium sulfate: dose : 4 gram
route :intravenous
frequency : stat
Control Intervention1: magnesium sulphate more than 4 gram: loading dose : 14 gram ( 4 gram intravenous followed
Sponsors
King Georges Medical University
Eligibility
Inclusion criteria
Inclusion criteria: Women with established preterm labour (regular uterine contraction with cervical dilatation of �4 cm )at gestational age of less than 32 weeks. 2. Women requiring iatrogenic preterm labour / cesarean at gestatonal age less than 32 weeks 3. Women with severe pre-Eclampsia or Eclampsia having preterm labour being given magnesium sulphate at less than 32 weeks .
Exclusion criteria
Exclusion criteria: 1. Myasthenia gravis 2. Acute renal failure 3. False preterm 4. Gestational age more than 32 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| apgar, need mechanical ventilation/ tracheal Intubation, seizures, Necrotizing enterocolitis, NICU admission, intraventricular hemorrhage, periventricular leucomalacia, white matter injury Fetal imaging : USG / MRI Timepoint: Fetal outcome : apgar, need mechanical ventilation/ tracheal Intubation, seizures, Necrotizing enterocolitis, NICU admission, intraventricular hemorrhage, periventricular leucomalacia, white matter injury Fetal imaging : USG / MRI | — |
Secondary
| Measure | Time frame |
|---|---|
| To document long term effect (cerebral palsy, neurodevelopment delay)Timepoint: 2 yrs | — |
Countries
India
Contacts
Public ContactNamrata Kumar
King Georges Medical University
Outcome results
None listed