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Oral medication for Pyorrhoea

The Adjunctive use of systemic antioxidant therapy (lycopene) in non surgical treatment of chronic periodontitis:A clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019281
Enrollment
40
Registered
2019-05-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A488- Other specified bacterial diseases

Interventions

Intervention1: Lycopene: Lycopene tablets commercially available as Zenith Nutrition Lycopene 10000 (6%) shall be used. Patients in Group A shall be asked to take one tablet of 6% (10000 micro gm) a d

Sponsors

Triveni Institute of Dental Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy patients with the age range of 30 to 60 years Presence of 12 or more scorable teeth Atleast 30% of teeth having pocket dept of 5 mm or more Clinical attachment loss to be moderate to severe Gingival index of 1 or more Plaque index of 1.5 or more

Exclusion criteria

Exclusion criteria: Subjects with any systemic illness Smokers or tobacco chewers Pregnant or lactating mothers Patients with prosthesis or orthodontic applicance Patients on medications like antibiotics antioxidants History of periodontal treatment in past 3 months prior to study

Design outcomes

Primary

MeasureTime frame
Decrease in pocket depth,attachment loss and gingival inflammation with usage of lycopeneTimepoint: 4 weeks

Secondary

MeasureTime frame
Improvement in salivary uric acid levels after scaling rootplaning and lycopene therapyTimepoint: 4 weeks

Countries

India

Contacts

Public ContactDr Raja S

Triveni Institute of Dental Sciences Hospital and Research Centre

drrajasridhar@rediffmail.com9329729790

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026