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"Comparing 0.1% Ropivacaine and 0.0625% Bupivacaine, with fentanyl for labour pain relief"

"Comparison of 0.1% Ropivacaine and 0.0625% Bupivacaine, with fentanyl as an adjuvant for labour analgesia"

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019271
Enrollment
40
Registered
2019-05-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 1- Obstetrics

Interventions

Intervention1: 0.1% of Ropivacaine: 0.1% of Ropivacaine with 2 micrograms/ml fentanyl as an adjuvant for epidural labour analgesia. Loading dose of 10ml after 4cm of cervical dilatation. Epidural top

Sponsors

G Ranganaayaki
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Parturients requesting epidural analgesia in SMVMCH from May 2019 to September 2020 2. Parturients of ASA physical status 1 and 2 3.Parturients in active labour with cervical dilation of more than 3 cm 4. Full term live fetus without any obstetric complication

Exclusion criteria

Exclusion criteria: 1) Height 2) BMI >30 3) Age 4) Anticipated difficult intubation 5) Contraindications for epidural catheter placement 6) Hyper-sensitivity to study drugs. 7) Administration of IV analgesics within 1hr of epidural request

Design outcomes

Primary

MeasureTime frame
Pain reliefTimepoint: Visual analog scale score will be recorded every 5 min for first 30 min, then at every 30 min till the end of labor. VAS at the end of the first stage and second stage is also noted.

Secondary

MeasureTime frame
maternal sedation sensory blockade motor blockadeTimepoint: Maternal sedation will be assessed using modified Ramsay sedation score. Motor block will be assessed by Bromage scale and peak motor block achieved during study is noted. Sensory block will be assessed by loss of cold sensation in midclavicular line, every 30 min and peak sensory level achieved during the study will be noted down. Fetal heart rate will be recorded throughout the study; neonatal welfare will be assessed by Apgar score.

Countries

India

Contacts

Public ContactG Ranganaayaki

Professor

drkrishnaprabu@gmail.com9943770977

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026