Health Condition 1: O754- Other complications of obstetric surgery and procedures
Conditions
Interventions
Intervention1: In Preeclamptic pregnant patients with magnesium sulfate therapy: Titrated dose of intravenous oxytocin infusion: The dose of the infusion will be 18 IU/h (i.e., 0.29 IU/min) for the fi
Sponsors
UCMS and GTBH
Eligibility
Inclusion criteria
Inclusion criteria: All laboring parturients >18 years age who have received oxytocin for labor induction and/or augmentation, whether preeclamptics who are receiving magnesium sulfate therapy (posted for cesarean section under spinal block/general anaesthesia) or normotensives without magnesium sulfate therapy( posted for cesarean section under spinal block) will be enrolled.
Exclusion criteria
Exclusion criteria: Exclusion criteria will include patient refusa, history of PPH or more than one previous uterine surgery as well as bleeding disorders, and presence of abnormal placentation, uterine fibroid. Those with any contraindication to spinal block such as hemodynamic instability, infection at site of injection, coagulopathy (thrombocytopenia with platelet count <100,000/mm3) etc. will also be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The calculated ED90 of prophylactic oxytocin infusion in both cohorts.Timepoint: The status of uterine tone assessed by the operating obstetrician (satisfactory or unsatisfactory) at 4-minute post-oxytocin initiation. | — |
Secondary
| Measure | Time frame |
|---|---|
| The requirement of additional uterotonic drugs.Timepoint: From cord clamping to end of surgery. | — |
Countries
India
Contacts
Public ContactDr Asha Tyagi
Department of Anaesthesiology and Critical Care
Outcome results
None listed