FindTrial
Sign In

A comparative evaluation between giving Dexamethasone in aerosol form and Magnesium sulphate in aerosol form and assessing whether it prevents post operative sore throat in patients undergoing surgeries in prone position. A prospective randomized double blind study.

A comparative evaluation of preoperative nebulised Dexamethasone and nebulised Magnesium sulphate on post operative sore throat in prone position surgeries. A prospective randomized double blind study.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019262
Enrollment
80
Registered
2019-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M498- Spondylopathy in diseases classified elsewhere

Interventions

Control Intervention1: Magnesium Sulphate: Aerosol route(nebulisation), magnesium sulphate 250 mg in normal saline making total volume 5 ml, given preoperatively before induction of anaesthesia and a

Sponsors

Pondicherry institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American society of Anesthesiologists (ASA) physical status 1 (normal healthy patient ) and ASA 2 (patient with mild systemic disease ) 2. Age between 20 to 60 years 3. Surgeries in prone position under general anaesthesia 4. Duration of surgery less than 3 hours

Exclusion criteria

Exclusion criteria: 1. Patients having history of preoperative sore throat or recent upper airway infection ,asthma ,chronic obstructive pulmonary disease 2. Pregnant woman 3. Mallampati grade > II ( anticipated difficult airway ) 4. Known allergies to study drug 5. Patients on chronic medication (NSAID,STEROIDS) 6. Those who require more than one attempt at intubation or traumatic intubation 7. Known smoker 8. Time of intubation > 60 seconds

Design outcomes

Primary

MeasureTime frame
To compare the effect of nebulised dexamethasone vs nebulised magnesium sulphate on the incidence of post operative sore throat in prone position surgeriesTimepoint: sore throat will be assessed at immediate post op , after 4 hours, 6 hours, and 24 hours—

Secondary

MeasureTime frame
To grade the severity of POST between the two groups To compare haemodynamic profiles between the two groups Timepoint: INTRAOPERATIVELY AT THE TIME OF INTUBATION , 5 MINUTES AFTER INTUBATION , 10 MINUTES AND 15 MINUTES AFTER INTUBATION RESPECTIVELY—

Countries

India

Contacts

Public ContactManujkumar

Pondicherry institute of medical sciences

ranjanrv2005@gmail.com9600823772

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026