Skip to content

Difference between effectiveness of two desensitizing agents

The effect of two different desensitizing agents on Dentin hypersensitivity: A randomized split mouth clinical trail. - DH trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019252
Enrollment
30
Registered
2019-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K038- Other specified diseases of hard tissues of teeth

Interventions

Intervention1: Profluorid Varnish: Fluoride Amount- 1 drop Frequency- once per week Route of administration - oral topical application on tooth Duration - 1 week Control Intervention1: UNO: Bio-active

Sponsors

A R Pradeep kumar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients with good general health, within 18-60years of age, with dentin hypersensitivity in at least one tooth in any two quadrants and exhibiting pain scores of two or more on the Visual Analogue Scale (VAS) were included in the study

Exclusion criteria

Exclusion criteria: Patients who were receiving or had received periodontal treatment within the past three months; used desensitizing treatment within past 6 months; using anti inflammatory, analgesic, psychotropic, or anti-depressant drugs: were pregnant or lactating; were allergic to any of the components in the desensitizing agents used in the study; and patients with eating disorders were excluded. Additionally, teeth with carious lesions, cracked/fractured teeth or teeth that required restorative treatment were excluded

Design outcomes

Primary

MeasureTime frame
To investigate the clinical efficacy of two different desensitizing agents i.e., Profluorid Varnish (Voco, Cuxhaven, Germany) and Uno Topical Gel (Germiphene, Brantford, Canada) in reducing dentin hypersensitivity immediately after application and after 1 week.Timepoint: Immediately after application and after 1 week.

Secondary

MeasureTime frame
To investigate the clinical efficacy of two different desensitizing agents i.e., Profluorid Varnish (Voco, Cuxhaven, Germany) and Uno Topical Gel (Germiphene, Brantford, Canada) in reducing dentin hypersensitivity among which either one of the material is better.Timepoint: Immediately after application and after 1 week.

Countries

India

Contacts

Public ContactA R Pradeep kumar

Thai moogambigai dental college and hospital

arpradeependo@gmail.com9840135711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026