Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Isoflurane With Nitrous Oxide: Will be maintained with Isoflurane , 50 % Nitrous Oxide and 50% Oxygen to maintain Minimum Alveolar Concentration ( MAC ) of 1
Control Intervention1: Isof
Sponsors
Dr Ajithkumar Pillai
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiologists Physical Status ( ASAPS ) l and ll scheduled for elective standardized surgeries under general anaesthesia with muscle relaxation requiring endotracheal intubation
Exclusion criteria
Exclusion criteria: Patients with severe cardio pulmonary diseases Laparoscopic surgeries Pregnant women Obese patients The presence of any gas filled , space occupying lesion Surgery duration less than 2 hours Patients with anticipated blood loss of more than 20 % of volume and hypothermia Neuromuscular disorders , hearing disabilities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the fall in Minimum Alveolar Concentration ( MAC ) with respect to time , time to extubation , eye opening , following commands , orientation at the time of extubation of Isoflurane with Nitrous Oxide and without Nitrous OxideTimepoint: For every minute for 5 minutes and every 5 minutes for 15 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the intra operative recall following Isoflurane based low flow anaesthesia with Nitrous Oxide and without Nitrous OxideTimepoint: After the surgery | — |
Countries
India
Contacts
Public ContactDr Najma Hassan
Kasturba Medical College
Outcome results
None listed