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Evaluation of effect of saline flush on the action of Rocuronium

Evaluation of effect of saline flush on time of onset and duration of action following bolus dose of rocuronium

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019208
Enrollment
82
Registered
2019-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K808- Other cholelithiasis

Interventions

Intervention1: ROCURONIUM BROMIDE: 0.6mg per kg of Lean Body weight Intravenous Control Intervention1: Rocuronium with normal saline: Rocuronium 0.6mg per kg of Lean Body weight with 20 ml normal sali

Sponsors

Vineet Manchanda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grading 1 and 2 . 2. BMI 3. Patients undergoing elective surgeries under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Pre existing neurological and neuromuscular disorders. 2. Pre existing cardiovascular disease. 3. Known liver and kidney disease. 4. Contraindication or previous adverse response to any of the study drugs. 5. Patients on any drugs known to interfere with the metabolism of NDMR. 6. Patients with documented electrolyte disorders.

Design outcomes

Primary

MeasureTime frame
The effect of saline flush vs no saline flush on duration of action of bolus dose of rocuronium taken till the appearance of first twitch.Timepoint: 1 year—

Secondary

MeasureTime frame
The effect of saline flush vs. no saline flush on 1. Time of onset of muscle relaxation taken when TOF reaches zero. 2. Intubating conditions when TOF reaches zero.Timepoint: 1 year—

Countries

India

Contacts

Public ContactDr Kirti Nath Saxena

LOK NAYAK HOSPITAL AND MAULANA AZAD MEDICAL COLLEGE

kirtinath@gmail.com9968604215

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026