FindTrial
Sign In

Study to see whether the addition of a medicine to the routine medicine will help in preventing vomiting after breast surgeries

A double blind randomized control study to compare the antiemetic efficacy of ondansetron versus ondansetron and dexamethasone combination in patients undergoing breast surgeries.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019171
Enrollment
72
Registered
2019-05-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: ondansetron: Group 1: patients will receive 0.1mg/kg iv of Inj. Ondansetron. Control Intervention1: dexamethasone: group 2 receives 0.1mg/kg of dexamethasone plus 0.1 mg/kg of ondansetr

Sponsors

Bangalore Baptist Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All females belonging to ASA I and II undergoing breaast surgeries

Exclusion criteria

Exclusion criteria: 1.Patients on chronic steroid therapy , 2.pregnant/lactating women, 3.patients having history of motion sickness 4.patients on preoperative chemotherapy , 5.patients having received antiemetic ,steroid within 24hrs of surgery 6.patients suffering from diabetes mellitus, intestinal obstruction, hiatus hernia, hepatic and renal diseases 7.patients with prolonged QTC interval

Design outcomes

Primary

MeasureTime frame
Nausea and vomitingTimepoint: within 24hrs after breast surgeries.—

Secondary

MeasureTime frame
to assess the need for resscue antiemetic in 24hrs after breast surgeryTimepoint: within 24hours—

Countries

India

Contacts

Public ContactDr Reena R Kadni

BANGALORE BAPTIST HOSPITAL

docreena1@gmail.com8197201890

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026