A study to find the ideal concentration of Propofol which is used for sedation by a special pump for taking biopsy from the uterus

Estimation of median effective effector site concentration (EC50)during target controlled infusion of propofol for dilatation and curettage-A prospective observational study

Status

Active, not recruiting

Phases

Phase 2

Study type

Observational

Source

CTRI

Registry ID

CTRI/2019/05/019151

Enrollment

Registered

2019-05-15

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N80-N98- Noninflammatory disorders of female genital tract

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: ASA1 and 2 patients 40 to 70 years age group

Exclusion criteria

Exclusion criteria: Patient refusal for sedation. Patients with risk of aspiration. Patients with reactive airway disease. Difficult airway. Obesity BMI more than 35. Patients with allergic to study drugs

Design outcomes

Primary

Measure	Time frame
To study adequacy of anaesthesia by patient movement with varied effector site concentration of Propofol. To study hemodynamic and respiratory changes with varied effector site concentration of Propofol. To identify surgical step that produces maximum stimulus by recording surgical step at which patient moves(holding of cervix, cervical dilatation, curettage of endometrium)Timepoint: 3 years	—

Secondary

Measure	Time frame
To measure plasma concentration of Propofol and to compare with calculated plasma concentration in TCI pumpTimepoint: 3 years	—

Countries

India

Contacts

Public ContactHemanth Kumar VR

Mahatma Gandhi Medical College and Research Institute

drvrhk@gmail.com9003550553

Outcome results