safety and efficacy of chlorprocaine(1%) vs chlorprocaine(1%) with 20 microgram fentanyl in subar achnoid block in lower limb ambulatory surgery

EVALUATION OF SAFETY AND EFFICACY OF CHLORPROCAINE (1%) V/S CHLORPROCAINE (1%) WITH 20 MICROGRAM FENTANYL IN SUBARACHNOID BLOCK IN PARTICIPANTS UNDERGOING LOWERLIMB SURGERY. A PROSPECTIVE, RANDOMIZED, DOUBLE BLIND CLINICAL TRIAL.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/05/019143

Enrollment

100

Registered

2019-05-15

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue

Interventions

Intervention1: Injection Chlorprocaine(1%), injection Fentanyl: patient recieved single injection of 4 ml (40 mg) of Chlorprocaine (1%) with 0.4 ml of Fentanyl (20 microgram) (Toatal volume of 4.4 ml)

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade: I, II, III Participants undergoing lower limb surgery under subarachnoid block duration of surgery-30 to 45 minutes patients giving written and informed consent

Exclusion criteria

Exclusion criteria: Participants not giving written and informed consent participantants not willing for subarachnoid block participants having contraindications to subarachnoid block like congenital spinal anomalies, altered coagulation profile, local site skin infection participants having severe psychiatric disorders like depression and dementia paricipants having neurological disease like brain tumour, cNS syphilis, meningitis spinal cord and peripheral nerve disease, poliomyelitis, multiple sclerosis participants with allergy to local anaesthetic drug drug, alcohol abuse prenancy lactationg mother chronic headache eg. migraine

Design outcomes

Primary

Measure	Time frame
To compare onset, peak time and duration of sensory, motor block in both groupsTimepoint: from the time of onset to achievment of peak effect	—

Secondary

Measure	Time frame
To measure effect of drug on hemodynamics, complication of drugs and technique, total duration of post operative analgesia and need of resque analgesia within 24 hoursTimepoint: time from subarachnoid injection to first dose of resque analgesic	—

Countries

India

Contacts

Public ContactDr Dhruvika N Viradiya

Department of Anaesthesia,Govt.medical college,Bhavnagar

drshilpadoshi@yahoo.in09428810763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026