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To Detect changes in biological samples during cancer progression using advanced optical instruments

Objective assessment of mitochondrial proteins in-vitro during oral cancer progression by combined Laser Induced Fluorescence (LIF) and Photoacoustic spectroscopy (PAS) measurements - LIF, PAS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/05/019129
Enrollment
50
Registered
2019-05-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

None listed

Sponsors

ICMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed with malignant or premalignant oral cancer

Exclusion criteria

Exclusion criteria: Individual with other diseases beside oral cancer

Design outcomes

Primary

MeasureTime frame
mitochondrial status can be during the progression of oral cancer using spectroscopy tool LIF and PAS toolsTimepoint: 1 year—

Secondary

MeasureTime frame
A.Minimal invasive approach in isolating mitochondria B.Sensitive and simple tool to detect the mitochondrial changes during cancer progressionTimepoint: 1Year—

Countries

India

Contacts

Public ContactDr Shama Prasada K

Manipal Academy of Higher Education

raghuram.manipal@gmail.com9901723049

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026