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Comfort during Bronchoscopy procedure

A Randomized controlled trial to evaluate the efficacy of topical pharyngeal anaesthesia using 5 vs 10 sprays of 10% lignocaine during flexible bronchoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019109
Enrollment
300
Registered
2019-05-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J851- Abscess of lung with pneumonia Health Condition 2: J168- Pneumonia due to other specified infectious organisms Health Condition 3: J981- Pulmonary collapse Health Condition 4: J99- Respiratory disorders in diseasesclassified elsewhere Health Condition 5: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: 10 sprays of 10% topical lignocaine: 10 sprays of 10% topical lignocaine would be applied on the pharynx prior to flexible bronchoscopy and the outcomes would be assessed Control Interv

Sponsors

Department of Pulmonary Medicine and Sleep Disorders
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adults more than or equal to 18 yrs of age undergoing flexible bronchoscopy

Exclusion criteria

Exclusion criteria: 1) Uncontrolled hypertension SBP >180 mm Hg 2) Symptomatic coronary artery disease 3) Pregnancy 4) Not giving informed consent for the procedure 5) Hypoxemia (oxygen saturation [by pulse oximetry] less than 92% with Fio2 ofmore than or equal to 0.3 6) Bronchoscopy performed through an artificial airway

Design outcomes

Primary

MeasureTime frame
Operator rated overall procedure satisfaction on Visual Analogue scale (VAS)Timepoint: At study completion approximately 12 months

Secondary

MeasureTime frame
1) Operator rated cough on VAS 2) Time from introduction to reaching the vocal cords 3) Patient willingness to return for repeat bronchoscopy 4) Cumulative lignocaine dose: Patients receiving more than 8.2 mg/kg, patients receiving more than 6 mg/kg lignocaine 5) Total dose of midazolam and fentanyl required 7) ComplicationsTimepoint: At study completion approximately 12 months

Countries

India

Contacts

Public ContactDr Karan Madan

AIIMS New Delhi

drkaranmadan@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026