Health Condition 1: J980- Diseases of bronchus, not elsewhere classified
Conditions
Interventions
Intervention1: GROUP A: Bilevel positive airway pressure delivering peak inspiratory pressure of 15cm of H2O, peak end expiratory pressure of 5cm of H2O by face mask with rate dependent on age, oxygen
Sponsors
NONE
Eligibility
Inclusion criteria
Inclusion criteria: CHILDREN PRESENTING TO THE PEDIATRICS EMERGENCY OR OUT PATIENT DEPARTMENT WITH ACUTE EXACERBATION DEFINED AS TACHYPNEA,HISTORY OF PREVIOUS SIMILAR EPISODES AND WHEEZING
Exclusion criteria
Exclusion criteria: 1.Children presenting with respiratory failure requiring immediate endotracheal intubation and assisted ventilation 2.Children with physician diagnosed bronchiolitis defined as the coryzal prodrome lasting 1 to 3 days followed by the persistence of cough and either tachypnea/chest recession and either wheeze/crackles on auscultation 3.Clinical suspicion of bacterial pneumonia:focal crackles or bronchial breathing and/or major chest x ray finding [consolidation,major infiltrates,pleural effusion] 4.Any contraindication to NIV use including altered mental status, recent bowel surgery,intractable vomiting,inability to protect airway 5.Current tracheostomy,home ventilation[IPPV or NIPPV]or home oxygen requirement 6.Receiving maintenance dose of oral steroid at time of hospital admission 7.History of congenital heart disease or chronic heart disease [including bronchopulmonary dysplasia,cystic fibrosis,pulmonary hypertension] 8.Craniofacial abnormality 9.pneumothorax at present
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Length of the time to reach pram score less than 3Timepoint: Assessment every hourly till pram score is less then 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Length of time to achieve hospital discharge criteria 2.Time to room air respiration 3.Comparison of bronchodilator requirement between groups [ median number of intravenous infusion hours,total salbutamol doses per patient per admission ,median doses of salbutamol per day] 4.Each group that require intubation and invasive ventilation 5.Each group experiencing significant treatment related side effects 6.Each group requiring hospital readmission within 48 hours of dischargeTimepoint: Assessment every hourly | — |
Countries
India
Contacts
Public ContactTARUN AHUJA
PGIMER
Outcome results
None listed